Types of PGT

PGT-A (CHROMOSOMAL ABNORMALITIES)

This allows the detection of the chromosomal makeup of embryos. Chromosomal abnormalities can be the cause of embryo implantation failure, recurrent miscarriages, and syndromes related to chromosomal disorders.

• Women over 37 years old with their own oocytes.

• Chromosomal abnormalities in semen: pathological FISH diagnosis.

• Recurrent miscarriages (2 or more).

• Severe oligozoospermia diagnosis in men.

• Long-term infertility.

PGT-SR (STRUCTURAL ABNORMALITIES)

PGT-SR is recommended for patients with chromosomal abnormalities.
Human body cells (except gametes) present 23 pairs of chromosomes. A percentage of the population has:

• Chromosomal translocations (swapped chromosomes)

• Chromosomal inversions (inverted chromosomes)

• Chromosomal deletions (missing small segments of a chromosome)

• Other chromosomal abnormalities
  In most of these cases, the person is healthy, but their reproduction may be affected, leading to a higher number of miscarriages or births with chromosomal rearrangements. The PGT-SR study allows for the selection of embryos without chromosomal alterations.

PGT-M (MONOGENIC DISEASES)

This is performed in patients who are carriers or affected by monogenic genetic diseases (e.g., cystic fibrosis). This type of PGT allows the selection of embryos that have not inherited the genetic component responsible for the disease.